The Lancet, Early Online Publication, 25 June 2011
Summary
Background
Data for previous termtrendsnext term in glycaemia and previous termdiabetes
prevalencenext term are needed to understand the effects of diet and lifestyle
within populations, assess the performance of interventions, and plan previous
termhealthnext term services. No consistent and comparable previous termglobal
analysis of trendsnext term has been done. We estimated previous
termtrendsnext term and their uncertainties in mean previous termfasting plasma
glucosenext term (FPG) and previous termdiabetes prevalencenext term for adults
aged 25 previous termyearsnext term and older in 199 previous termcountriesnext
term and territories.
Methods
We obtained data from previous termhealth examination surveys and
epidemiological studies (370 country-years and 2·7 million participants)next term.
We converted systematically between different glycaemic metrics. For each sex,
we used a Bayesian hierarchical model to estimate mean FPG and its uncertainty
by age, previous termcountry, and year,next term accounting for whether a previous
termstudynext term was nationally, subnationally, or community representative.
Findings
In 2008, previous termglobalnext term age-standardised mean FPG was 5·50
mmol/L (95% uncertainty interval 5·37–5·63) for men and 5·42 mmol/L (5·29–5·54)
for women, having risen by 0·previous term07next term mmol/L and 0·09 mmol/L
per decade, respectively. Age-standardised adult previous termdiabetes
prevalencenext term was 9·8% (8·6–11·previous term2)next term in men and 9·2%
(8·0–10·5) in women in 2008, up from 8·3% (6·5–10·4) and previous term7next
term·5% (5·8–9·6) in previous term 1980.next term The number of people with
previous termdiabetesnext term increased from 153 (127–182) previous
termmillionnext term in previous term1980,next term to 347 (314–382) previous
termmillionnext term in 2008. We recorded almost no change in mean FPG in
east and southeast Asia and central and eastern Europe. Oceania had the largest
rise, and the highest mean FPG (6·09 mmol/L, 5·73–6·49 for men; 6·08 mmol/L,
5·72–6·46 for women) and previous termdiabetes prevalencenext term (15·5%,
11·6–20·1 for men; and 15·9%, 12·1–20·5 for women) in 2008. Mean FPG and
previous termdiabetes prevalencenext term in 2008 were also high in south Asia,
Latin America and the Caribbean, and central Asia, north Africa, and the Middle
East. Mean FPG in 2008 was lowest in sub-Saharan Africa, east and southeast
Asia, and high-income Asia-Pacific. In high-income subregions, western Europe
had the smallest rise, 0·previous term07next term mmol/L per decade for men
and 0·03 mmol/L per decade for women; North America had the largest rise,
0·18 mmol/L per decade for men and 0·14 mmol/L per decade for women.
Interpretation
Glycaemia and previous termdiabetesnext term are rising globally, driven both by
population growth and ageing and by increasing age-specific previous
termprevalences.next term Effective preventive interventions are needed, and
previous termhealthnext term systems should prepare to detect and manage
previous termdiabetesnext term and its sequelae.
TEXTO COMPLETO EN TIMBO COLECCION SCIENCE DIRECT
O SOLICITE EL TRABAJO A busquedas@smu.org.uy